Intra-Tumoral Hepatic Administration Under CT Stereotactic and Ultrasound Guidance of in Situ Anti-Cancer Agent Derived from [188re]Rhenium Nitro-Imidazole Ligand Loaded 5th Generation Poly-l-Lysine Dendrimer
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New Potential In Situ Anticancer Agent Derived from [188Re]rhenium Nitro-Imidazole Ligand Loaded 5th Generation Poly-L-Lysine Dendrimer for Treatment of Transplanted Human Liver Carcinoma in Nude Mice
Hepatocellular carcinoma (HCC) is the most common primary liver tumor and one of the fifth most common tumors worldwide. In this article we report the results of in vivo studies of potential anticancer agent "[188Re] rhenium-ImDendrim" derived from [188Re]rhenium-nitro-imidazole-methyl -1,2,3-triazol-methyl-di-(2-pycolyl)amine as radioactive ligand loaded 5th generation poly-L-lysine denrimer (...
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ژورنال
عنوان ژورنال: International Journal of Radiation Oncology*Biology*Physics
سال: 2019
ISSN: 0360-3016
DOI: 10.1016/j.ijrobp.2019.06.1106